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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TBL1XR1
All Species:
45.15
Human Site:
Y446
Identified Species:
66.22
UniProt:
Q9BZK7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BZK7
NP_078941.2
514
55595
Y446
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Chimpanzee
Pan troglodytes
XP_521379
534
57733
Y456
M
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Rhesus Macaque
Macaca mulatta
XP_001101823
506
54482
Y438
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Dog
Lupus familis
XP_850905
514
55709
Y446
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHJ5
514
55642
Y446
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Rat
Rattus norvegicus
Q5M7T1
339
37599
A275
A
T
A
C
G
D
D
A
I
R
V
F
E
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516513
527
56747
Y459
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Chicken
Gallus gallus
NP_001153226
523
56567
Y455
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Frog
Xenopus laevis
Q6GPC6
522
56266
Y454
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
D
Zebra Danio
Brachydanio rerio
Q803D2
410
46511
F346
N
W
V
R
G
V
L
F
H
P
G
G
R
F
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95RJ9
700
72369
Y631
T
K
H
T
E
P
V
Y
S
V
A
F
S
P
D
Honey Bee
Apis mellifera
XP_393667
512
56104
Y443
T
K
H
T
E
P
V
Y
S
V
A
F
S
P
D
Nematode Worm
Caenorhab. elegans
Q17963
376
40375
G312
F
A
N
F
S
V
T
G
G
K
W
I
I
S
G
Sea Urchin
Strong. purpuratus
XP_001198347
493
53832
Y425
T
K
H
Q
E
P
V
Y
S
V
A
F
S
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FLX9
473
52879
S409
V
G
P
V
Y
Q
V
S
W
S
A
D
S
R
L
Baker's Yeast
Sacchar. cerevisiae
P38262
535
59143
K456
R
I
S
Q
D
G
Q
K
Y
A
V
A
F
M
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
96.8
99
N.A.
99
21
N.A.
88.8
90.2
96.7
22.1
N.A.
55.7
74.1
21.7
79.3
Protein Similarity:
100
89.1
97.4
99.4
N.A.
99.2
32.2
N.A.
93.5
94.8
97.3
38.5
N.A.
64.5
81.5
36.7
85.8
P-Site Identity:
100
93.3
100
100
N.A.
100
13.3
N.A.
100
100
100
0
N.A.
93.3
93.3
0
93.3
P-Site Similarity:
100
93.3
100
100
N.A.
100
13.3
N.A.
100
100
100
20
N.A.
93.3
93.3
6.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
26.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.1
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
0
7
0
7
75
7
0
0
0
% A
% Cys:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
7
7
0
0
0
0
7
0
0
75
% D
% Glu:
0
0
0
0
69
0
0
0
0
0
0
0
7
7
0
% E
% Phe:
7
0
0
7
0
0
0
7
0
0
0
75
7
7
0
% F
% Gly:
0
7
0
0
13
7
0
7
7
0
7
7
0
0
7
% G
% His:
0
0
69
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
0
7
0
0
0
0
0
0
7
0
0
7
7
0
0
% I
% Lys:
0
69
0
0
0
0
0
7
0
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
7
% L
% Met:
7
0
0
0
0
0
0
0
0
0
0
0
0
7
0
% M
% Asn:
7
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
7
0
0
69
0
0
0
7
0
0
0
69
0
% P
% Gln:
0
0
0
63
0
7
7
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
0
7
0
0
0
0
0
7
0
0
7
7
0
% R
% Ser:
0
0
7
0
7
0
0
7
69
7
0
0
75
7
7
% S
% Thr:
63
7
0
13
0
0
7
0
0
0
0
0
0
0
0
% T
% Val:
7
0
7
7
0
13
75
0
0
69
13
0
0
0
7
% V
% Trp:
0
7
0
0
0
0
0
0
7
0
7
0
0
0
0
% W
% Tyr:
0
0
0
0
7
0
0
69
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _